Table 1.

Hemodynamic Profiles and Mortality Risk for Pulmonary Hypertension in Sickle Cell Disease

	Precapillary PH	Postcapillary PH	PH with Features of Both Precapillary and Postcapillary PH
mPAP	≥ 25 mm Hg	≥ 25 mm Hg	≥ 25 mm Hg
PAWP or LVEDP	≤ 15 mm Hg	> 15 mm Hg	> 15 mm Hg
PVR	≥ 2 Wood Units	< 2 Wood Units	≥ 2 Wood Units
Survival	Reduced	Reduced	Reduced

LVEDP = left ventricular end-diastolic pressure; mPAP = mean pulmonary arterial pressure; PAWP = pulmonary arterial wedge pressure; PH = pulmonary hypertension; PVR = pulmonary vascular resistance.