Video 1. Vertical eye movements and ataxia features in Niemann-Pick Type C. The patient had relatively intact horizontal smooth pursuit, saccades, and optokinetic nystagmus. However, these eye movements in the vertical direction were impaired. In addition, the downward smooth pursuit was slower than the upward smooth pursuit. The patient also exhibited features of cerebellar ataxia as characterized by abnormal finger chase test, tandem walking, and gait ataxia.

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