Fig. 1.

Flow Diagram of Participants Disposition (CONSORT flow diagram). Note: d: mITT analysis set [excluded: 3 adults (2 withdrawn by participants’ own will and 1 lost follow-up) and 2 children (withdrawn by participants’ own will) in Test vaccine group, and 1 child (withdrawn by participants’ own will) in Comparator vaccine group], e: PP analysis set [excluded: 5 adults (1 withdrawn by own will, 1 outside visit window, and 3 recruited out of study area) and 8 children (1 withdrawn due to lost to follow-up, 1 missed vaccination due to safety issue, 4 spat out the vaccine, 1 was administered wrong IP, and 1 due to outside visit window) in Test vaccine group; 2 adults (1 missed vaccination due to pregnancy and 1 was recruited out of study area) and 3 children (1 missed vaccination due to SAE and 2 spat out) in Comparator vaccine group].