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. 2018 May 8;13:30–44. doi: 10.1016/j.molmet.2018.05.004

Figure 7.

Figure 7

Osteoglycin negatively correlates with fat and bone mass in mice. (A) Osteoglycin levels at cull in wildtype (WT) mice fed either a chow or HFD. Correlations between osteoglycin levels and (B) fat mass, (C) glucose levels, (D) insulin levels and (E) whole body BMC as well as correlation between (F) glucose levels and whole body BMC in WT mice fed either chow or HFD. (G) Body weight and (H) total white adipose tissue (WAT) mass in WT and Ogn−/− mice fed either a chow or HFD for 8 weeks. uCT analysis of the femora of WT or Ogn−/− mice fed either a chow or HFD showing (I) cortical bone volume, (J) cortical thickness, (K) periosteal perimeter, (L) polar MMI, (M) trabecular bone volume (BV/TV), (N) trabecular thickness, and (O) trabecular number. Data are means ± SEM of at least 7 per group, * = p < 0.05, ** = p < 0.01, *** = p < 0.001 as indicated.