Table 2.
Effect of selected plant extracts and fractions on PTP-1B and glucose uptake C2C12 muscle cells
| S. No. | Sample code | Extract/fractions |
% Stimulation on Glucose uptake |
% Inhibition of PTP-1B activity |
|||
|---|---|---|---|---|---|---|---|
| 10 μg/ml | 20 μg/ml | 10 μg/ml | 20 μg/ml | 50 μg/ml | |||
| 1 | MATE | Ethanol extract | +19.7 | +23.6 | 28.9 | 30.1 | 42.5 |
| 2 | MATH | Hexane fraction | +9.5 | +12.7 | 45.8 | 51.7 | 56.9 |
| 3 | MATC | Chloroform fraction | +11.2 | +14.8 | 37.9 | 44.1 | 49.4 |
| 4 | MATB | Butanol fraction | +23.4 | ND | 57.6 | 72.0 | 68.5 |
| 5 | ZALE | Ethanol extract | Nil | +8.4 | 47.8 | 45.7 | 56.8 |
| 6 | ZALH | Hexane fraction | +6.3 | +9.1 | 41.9 | 48.5 | 56.9 |
| 7 | ZELC | Chloroform fraction | +9.2 | +14.7 | 49.2 | 56.7 | 59.2 |
| 8 | ZALB | Butanol fraction | +17.8 | ND | 61.9 | 70.9 | 71.5 |
| 9 | TNLE | Ethanol extract | +61.2 | +41.9 | 60.7 | 71.3 | 70.1 |
| 10 | TNLH | Hexane fraction | +8.7 | +17.3 | 40.3 | 48.8 | 56.2 |
| 11 | TNLC | Chloroform fraction | +13.2 | +15.8 | 53.4 | 58.1 | 66.2 |
| 12 | TNLB | Butanol fraction | +41.2 | ND | 59.6 | 63.8 | 64.4 |
Ethanol extract (E); Hexane fraction (H); Chloroform fraction (C); Butanol fraction (B); MATE: Melia Azadarach Twigs Ethanol; MATH: Melia Azadarach Twigs Hexane; MATC: Melia Azadarach Twigs Chloroform; MATB: Melia Azadarach Twigs Butanol; ZALE: Zanthoxylum Elatum Leaves Ethanol; ZALH: Zanthoxylum Elatum Leaves Hexane; ZALC: Zanthoxylum Elatum Leaves Chloroform; ZALB: Zanthoxylum Elatum Leaves Butanol; TNLE: Tanacetum Nubigenum Leaves Ethanol; TNLH: Tanacetum Nubigenum Leaves Hexane; TNLC: Tanacetum Nubigenum Leaves Chloroform; TNLB: Tanacetum Nubigenum Leaves Butanol