Rg3-RGE attenuated serum glucose and liver biomarker levels in LDL–/– mice. (A–C) Serum glucose, GOT, and GPT levels were determined using an ELISA kit after oral treatment of the mice with Rg3-RGE over 4 wk. Bar graphs represent means ± SEM (n = 6). A p value of <0.05 was considered significant compared with the atorvastatin group (positive control). (D) This figure part represents the following: (a) normal liver section of mice treated with regular chow diet; (b) LDL–/– mice fed with a western diet for 12 wk; (c) LDL–/– mice treated with atorvastatin at 5 mg/kg as positive control; and LDL–/– mice given Rg3-RGE at (d) 2.5 mg/kg and (e) 5 mg/kg. GOT, glutamic-oxaloacetic transaminase; GPT, glutamate-pyruvate transaminase; LDL, low-density lipoprotein; Rg3-RGE, Rg3-enriched red ginseng extract; SEM, standard error of the mean.