Table 3.
Results of the non-response analyses for follow-up measurements
| T1 Responders (n = 180)a |
T1 Non-responders (n = 56)a |
p-value | T2 Responders (n = 170)a |
T2 Non-responders (n = 67)a |
p-value | T3 Responders (n = 162)a |
T3 Non-responders (n = 77)a |
p-value | T4 Responders (n = 165)a |
T4 Non-responders (n = 74)a |
p-value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | |||||
| Health state (baseline scores) | ||||||||||||
| Complaints intensity in previous week (NRS) [0–10] mean (sd) | 4.18 (2.3) | 3.48 (2.2) | 0.119 | 4.06 (2.3) | 4.0 (2.3) | 0.905 | 4.13 (2.2) | 3.71 (2.16) | 0.307 | 4.05 (2.27) | 4.03 (2.31) | 0.954 |
| Disability (DASH) [0–100] mean (sd) | 15.3 (12.5) | 12.6 (12.5) | 0.393 | 15.4 (12.7) | 12.3 (10.8) | 0.234 | 14.9 (12.6) | 15.5 (12.3) | 0.808 | 14.6 (12.1) | 16.9 (14.1) | 0.339 |
| Impact participation and autonomy (IPA), | ||||||||||||
| Autonomy indoors [0–4] mean (sd) | 0.21 (0.36) | 0.95 (0.12) | 0.065 | 0.18 (0.32) | 0.21 (0.41) | 0.657 | 0.16 (0.31) | 0.18 (0.27) | 0.879 | 0.16 (0.30) | 0.32 (0.41) | 0.065 |
| Family role [0–4] mean (sd) | 0.50 (0.57) | 0.60 (0.79) | 0.545 | 0.52 (0.55) | 0.44 (0.83) | 0.714 | 0.49 (0.54) | 0.59 (0.50) | 0.522 | 0.46 (0.53) | 0.74 (0.82) | 0.095 |
| Autonomy outdoors [0–4] mean (sd) | 0.57 (0.62) | 0.71 (0.58) | 0.413 | 0.57 (0.59) | 0.61 (0.86) | 0.844 | 0.53 (0.59) | 0.59 (0.47) | 0.752 | 0.55 (0.60) | 0.68 (0.68) | 0.373 |
| Social life and relationships [0–4], mean (sd) | 0.45 (0.48) | 0.43 (0.57) | 0.879 | 0.50 (0.48) | 0.28 (0.45) | 0.096 | 0.48 (0.50) | 0.55 (0.55) | 0.621 | 0.46 (0.48) | 0.36 (0.44) | 0.323 |
| Work and education [0–4] mean (sd) | 0.87 (0.71) | 0.80 (0.67) | 0.757 | 0.89 (0.70) | 0.59 (0.73) | 0.119 | 0.86 (0.71) | 0.96 (0.59) | 0.622 | 0.82 (0.69) | 0.83 (0.69) | 0.801 |
| Duration of complaints at baseline | 0.246 | 0.371 | 0.151 | 0.697 | ||||||||
| < 3 mo | 105 (58.3) | 28 (51.9) | 95 (55.9) | 38 (59.4) | 96 (60.0) | 37 (50.0) | 94 (57.7) | 39 (54.9) | ||||
| ≥ 3 mo | 75 (41.7) | 26 (48.1) | 75 (44.1) | 26 (40.6) | 64 (40.0) | 37 (50.0) | 69 (42.3) | 32 (45.1) | ||||
| History of CANS | 0.208 | 0.151 | 0.062 | 0.264 | ||||||||
| No | 20 (15.3) | 2 (6.1) | 20 (15.5) | 31 (88.6) | 16 (13.9) | 6 (12.2) | 15 (12.8) | 7 (14.9) | ||||
| Yes, one time before | 15 (11.5) | 2 (6.1) | 15 (11.6) | 2 (5.7) | 16 (13.9) | 1 (2.0) | 15 (12.8) | 2 (4.3) | ||||
| Yes, more times before | 96 (73.3) | 29 (87.9) | 94 (72.9) | 31 (88.6) | 83 (72.2) | 47 (85.7) | 87 (74.4) | 38 (80.9) | ||||
| Frequency of discomfort of complaints | 0.729 | 0.862 | 0.581 | 0.792 | ||||||||
| No discomfort | 1 (0.8) | 0 (0.0) | 1 (0.8) | 0 (0.0) | 1 (0.9) | 0 (0.0) | 1 (0.8) | 0 (0.0) | ||||
| Regularly | 94 (70.7) | 26 (76.5) | 93 (71.5) | 27 (73.0) | 81 (69.8) | 39 (76.5) | 84 (71.2) | 36 (73.5) | ||||
| Almost continuously | 38 (28.6) | 8 (23.5) | 36 (27.7) | 10 (27.0) | 34 (29.3) | 12 (23.5) | 33 (28.0) | 13 (26.5) | ||||
| Personal factors | ||||||||||||
| Gender (female) | 133 (73.5) | 44 (78.6) | 0.555 | 127 (74.7) | 50 (74.6) | 0.990 | 121 (75.6) | 56 (72.7) | 0.631 | 123 (75.5) | 54 (73.0) | 0.683 |
| Age (years), mean (sd) | 36.1 (13.4) | 33.5 (12.9) | 0.193 | 36.8 (13.5) | 32.2 (12.4) | 0.014 | 35.9 (13.4) | 34.4 (13.1) | 0.421 | 36.5 (13.8) | 33.3 (11.8) | 0.069 |
| Paid work | 119 (65.7) | 28 (50.0) | 0.050 | 114 (67.1) | 33 (49.3) | 0.017 | 102 (63.7) | 45 (58.4) | 0.430 | 103 (63.2) | 44 (59.5) | 0.583 |
| Student status | 62 (34.3) | 28 (50.0) | 56 (32.9) | 34 (50.7) | 58 (36.3) | 32 (41.6) | 60 (36.8) | 30 (40.5) | ||||
| Marital status | 0.175 | 0.102 | 0.728 | 0.878 | ||||||||
| Unmarried/ living alone | 58 (34.9) | 10 (55.6) | 54 (34.2) | 14 (53.8) | 57 (37.7) | 11 (33.3) | 56 (36.8) | 12 (37.5) | ||||
| Married/ living together | 99 (59.6) | 8 (44.4) | 95 (60.1) | 12 (46.2) | 86 (57.0) | 21 (63.3) | 88 (57.9) | 19 (59.4) | ||||
| Widow/ divorced | 9 (5.4) | 0 (0.0) | 9 (5.7) | 0 (0.0) | 8 () | 1 (3.0) | 8 (5.3) | 1 (3.1) | ||||
| Children in the household | 0.574 | 0.753 | 0.333 | 0.005 | ||||||||
| No | 144 (86.7) | 16 (88.9) | 138 (87.3) | 22 (84.6) | 133 (88.1) | 27 (81.8) | 137 (90.1) | 23 (71.9) | ||||
| Yes, one or more | 22 (13.3) | 2 (11.1) | 20 (12.7) | 4 (15.4) | 18 (11.9) | 6 (18.2) | 15 (9.9) | 9 (28.1) | ||||
| Sports participation (yes) | 81 (45.0) | 27 (50.0) | 0.623 | 77 (45.6) | 31 (47.7) | 0.441 | 78 (49.1) | 30 (40.0) | 0.195 | 74 (45.7) | 34 (47.2) | 0.827 |
| Meet Dutch Norm of Healthy Living (yes) | 112 (62.2) | 37 (68.5) | 0.495 | 110 (65.1) | 39 (60.0) | 0.282 | 102 (64.2) | 47 (62.7) | 0.826 | 103 (63.9) | 46 (63.9) | 0.964 |
| Participation | ||||||||||||
| Sick leave due to CANS | 0.036 | 0.360 | 0.044 | 0.357 | ||||||||
| Yes, < 1 mo | 4 (3.4) | 4 (14.3) | 5 (4.4) | 3 (9.1) | 4 (3.9) | 4 (8.9) | 4 (3.9) | 4 (9.1) | ||||
| Yes, ≥ 1 mo | 1 (0.8) | 1 (3.6) | 1 (0.9) | 1 (3.0) | 0 (0.0) | 2 (4.4) | 1 (1.0) | 1 (2.3) | ||||
| No | 114 (77.6) | 23 (82.1) | 108 (94.7) | 29 (87.9) | 98 (96.1) | 39 (86.7) | 98 (95.1) | 39 (88.6) | ||||
| Full-time work, n (%) | 86 (68.8) | 18 (64.3) | 0.811 | 83 (68.6) | 22 (66.7) | 0.833 | 71 (67.9) | 32 (68.1) | 0.984 | 76 (71.0) | 28 (60.9) | 0.217 |
| Working in current job, | 0.373 | 0.929 | 0.465 | 0.813 | ||||||||
| < 3 y | 45 (36.0) | 7 (25.0) | 41 (34.2) | 11 (33.3) | 38 (35.8) | 14 (29.8) | 37 (34.6) | 15 (32.6) | ||||
| ≥ 3 y | 80 (64.0) | 21 (75.0) | 79 (65.8) | 22 (66.7) | 68 (64.2) | 33 (70.2) | 70 (65.4) | 31 (67.4) | ||||
| Work-related complaints (yes) | 108 (89.3) | 21 (80.8) | 0.318 | 104 (89.7) | 25 (80.6) | 0.147 | 93 (89.4) | 36 (83.7) | 0.337 | 94 (89.5) | 35 (83.3) | 0.301 |
T Time point, T1 6 weeks follow-up, T2 12 weeks follow-up, T3 6 months follow-up, T4 12 months follow-up, NRS Numeric Rating Scale, DASH Disabilities of the Arm, Hand and Shoulder Questionnaire, IPA Impact on Participation and Autonomy Questionnaire, sd standard deviation, mo month(s), y year(s)
aTotal number of cases does not equal total study population due to missing values on complaint duration