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. 2018 Jun 30;23:29. doi: 10.1186/s12199-018-0719-y

Table 3.

Interaction between ALDH2 rs671 polymorphism and dessert intake on CAD risk

ALDH2 rs671 polymorphism genotype
Non-risk allele carriers (G/G) Risk allele carriers (A/A + A/G) OR (95% CI) for A/A + G/G within strata of dessert intake
N cases/controls OR (95% CI) N cases/controls OR (95% CI)
No dessert intake 15/101 22/71
1.0 1.950 (0.930–4.088)
P = 0.077
1.950 (0.930–4.088)
P = 0.077
Regular dessert intake 57/173 67/150
2.095 (1.113–3.944)
P = 0.022
2.539 (1.335–4.829)
P = 0.004
1.212 (0.773–1.901)
P = 0.402
OR (95% CI) for regular dessert intake within strata of genotype 2.095 (1.113–3.944)
P = 0.022
1.302 (0.727–2.331)
P = 0.374

Measure of interaction on additive scale: RERI (95% CI) = − 0.506 (− 2.110 to 1.099); P value = 0.537

Adjusted for age, sex, BMI, SBP, TC level, TG level, HDL-C level, current smoking, current alcohol intake, and history of diabetes mellitus

Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12