Table 3.
Interaction between ALDH2 rs671 polymorphism and dessert intake on CAD risk
| ALDH2 rs671 polymorphism genotype | |||||
|---|---|---|---|---|---|
| Non-risk allele carriers (G/G) | Risk allele carriers (A/A + A/G) | OR† (95% CI) for A/A + G/G within strata of dessert intake | |||
| N cases/controls | OR† (95% CI) | N cases/controls | OR† (95% CI) | ||
| No dessert intake | 15/101 | 22/71 | |||
| 1.0 | 1.950 (0.930–4.088) P = 0.077 |
1.950 (0.930–4.088) P = 0.077 |
|||
| Regular dessert intake | 57/173 | 67/150 | |||
|
2.095 (1.113–3.944)
P = 0.022 |
2.539 (1.335–4.829)
P = 0.004 |
1.212 (0.773–1.901) P = 0.402 |
|||
| OR† (95% CI) for regular dessert intake within strata of genotype |
2.095 (1.113–3.944)
P = 0.022 |
1.302 (0.727–2.331) P = 0.374 |
|||
Measure of interaction on additive scale: RERI (95% CI) = − 0.506 (− 2.110 to 1.099); P value = 0.537
†Adjusted for age, sex, BMI, SBP, TC level, TG level, HDL-C level, current smoking, current alcohol intake, and history of diabetes mellitus
Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12