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. Author manuscript; available in PMC: 2018 Jul 12.
Published in final edited form as: Nat Methods. 2018 Jan 1;15(2):107–114. doi: 10.1038/nmeth.4540

Figure 3.

Figure 3

Workflow for calculating mutation and variant enrichment using Interactome INSIDER (http://interactomeinsider.yulab.org). Users may submit mutations or select sets of known disease and cancer mutations to assess their enrichment in interface domains and residues, or may compute 3D atomic clusters of mutations in proteins and across interfaces.