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. 2018 Jul 2;9(6):166. doi: 10.1038/s41424-018-0033-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Patients with the presence of liver cirrhosis (a) were significantly more likely to develop late recurrence of HCC. Patients low LC3 expression in HCC tissues (−/+), adjacent non-tumor (ANT) tissues (+/−), or both (−/−) had a higher incidence of late recurrence than patients with LC3 expression in both HCC and ANT tissues (+/+; b). HCC hepatocellular carcinoma, ANT adjacent non-tumor, HR hazard ratio, CI confidence intervals, + high, − low