Table 4.
Demographics, summarized statistics (mean and standard deviations) and comparisons (p value) between premutation carrier converters and non-converters.
| Visit 1 | Visit 2 | |||||
|---|---|---|---|---|---|---|
| Converters | Non-Converters | p | Converters Mean | Non-Converters | p | |
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||
| MCP | 9.03 (0.85) | 10.2 (0.67) | 0.002 | 8.73* (0.74) | 10.1 (0.80) | 0.001 |
| SCP | 4.94 (0.55) | 5.31 (1.30) | 0.412 | 5.08 (0.70) | 5.18 (1.06) | 0.812 |
| Midbrain | 153.9 (25.9) | 173.4 (30.9) | 0.146 | 150.7 (23.0) | 170.3 (32.0) | 0.132 |
| Pons | 549.6 (65.4) | 616.4 (39.7) | 0.013 | 544.6 (68.8) | 618.4 (43.6) | 0.010 |
| MCP/SCP | 1.86 (0.32) | 2.02 (0.47) | 0.368 | 1.72 (0.36) | 2.00 (0.32) | 0.080 |
| Pons/Midbrain | 3.62 (0.44) | 3.65 (0.59) | 0.911 | 3.64 (0.41) | 3.73 (0.61) | 0.706 |
| MRPI | 6.74 (1.58) | 7.33 (1.94) | 0.470 | 6.29 (1.70) | 7.52 (1.96) | 0.151 |
Values in parentheses represent standard deviations. *Indicates that a paired samples t-test between visits is p = 0.032, and significant prior to correction for multiple comparisons.