DENV induces lower levels of FH than FB. HUVEC (A), MDM (B), HREC (C), and (D) ARPE-19 cells were isolated and were left uninfected (UI) or DENV infected. At 48 hpi, supernatants were analyzed by ELISA for FH and FB proteins, and the ratio between the two was calculated. A lower ratio implies lower levels of FH than FB. Results represent the mean ± standard deviation for duplicate samples and are representative of those from three independent infection experiments. *, P < 0.05, Student's unpaired t test.