Table 1.
Laboratory parameters and results of APACHE II-, and SOFA scores at inclusion, after 3, and 7 days in the septic- (SG, n = 51), septic survived- (SSG, n = 39), septic non-survived- (SNSG, n = 12), and CG (n = 48); (median/0.25–0.75 quartile).
| Values | At inclusion |
After 3 days |
After 7 days |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sepsis group (n = 51) |
CG (n = 48) | Sepsis group (n = 51) |
CG (n = 48) | Sepsis group (n = 51) |
CG (n = 48) | |||||||
| SG (all) | SSG | SNSG | SG (all) | SSG | SNSG | SG (all) | SSG | SNSG | ||||
| Lactate (mmol/l) | 1.7 (1.5–2.9)* | 1.7 (1.5–2.5)* | 2.4 (1.4–5.3)* | 1.1 (0.9–1.3) | 1.7 (1.2–2.4)* | 1.6 (1.2–2.2)* | 1.9 (1.8–3.4)* | 1.3 (0.9–1.6) | 1.4 (1.2–2.1) | 1.4 (1.1–2.0) | 2.2 (1.4–3.2) | 1.6 (1.3–2.8) |
| Bilirubin (μmol/l) | 19.9 (12.1–36.8)* | 19.2 (13.9–37.1)* | 21.4 (11.7–33) | 15.2 (11.3–18.8) | 15.7 (10.7–30.9)* | 15.0 (10.8–30.0)* | 21.5 (10.0–35.9)* | 11.0 (8.6–15.7) | 13.4 (9.1–24.3)* | 11.9 (8.6–23.9)* | 16.8 (12.3–27.8)* | 9.1 (7.6–10.8) |
| Ammonia (mmol/l) | 51.3 (34.5–63.9)* | 43.1 (30.9–60.4)* | 54.4 (43.0–68.7)* | 31.7 (22.4–39.4) | 49.3 (38.4–65.4)* | 48.1 (38.7–60.2)* | 50.4 (35.5–78.8)* | 31.8 (25.5–38.7) | 43.7 (37.3–59.2)* | 43.6 (36.8–59.8)* | 48.4 (38.3–80.2)* | 32.4 (24.0–43.5) |
| Creatinine (μmol/l) | 136 (94–202)* | 130 (93–193)* | 161 (103–245)* | 78 (66–94) | 130 (92–215)* | 127 (92–190)* | 148 (108–232)* | 77 (65–88) | 83 (64–165)* | 82 (62–155) | 95 (82–249)* | 79 (65–89) |
| Urea (mmol/l) | 10.5 (7.3–17.4)* | 9.4 (7.3–14.5)* | 17.3 (7.7–22.7)* | 4.4 (3.4–5.8) | 12.2 (7.9–18.1)* | 10.8 (7.0–15.1)* | 18 (11.4–26.7)* | 4.6 (3.3–5.5) | 11.3 (6.3–19.7)* | 11 (6.1–16.2)* | 18.6 (8.2–35.0)* | 4.5 (3.6–5.4) |
| PCT (ng/ml) | 12.2 (3.9–32.5)* | 10.5 (3.3–28.8)* | 18.2 (4.4–47.2)* | 0.5 (0.2–0.8) | 5.0 (2.0–15.7)* | 4.6 (2.0–12.5)* | 6.9 (2.2–24.0)* | 0.4 (0.1–0.6) | 0.7 (0.4–3.3)* | 0.7 (0.4–2.2)* | 4.6 (0.4–6.7)* | 0.2 (0.1–0.2) |
| Leukocytes (GpT/l) | 14.8 (9.1–23.0)* | 14.6 (8.2–22.1)* | 20.2 (11.8–51.5)* | 9.1 (7.6–11.7) | 12.6 (8.6–16.7)* | 11.6 (8.3–15.4)* | 14.6 (10.5–24.4)* | 8.9 (7.3–11.5) | 13.3 (11.0–18.3)* | 13.2 (10.4–17.7)* | 15.3 (12.4–25.3)* | 9.0 (8.0–10.9) |
| Thrombocytes (GpT/l) | 191 (106–254) | 201 (107–254) | 174 (65–248) | 184 (136–238) | 170 (100–244) | 187 (109–256) | 149 (71–189)* | 187 (149–252) | 229 (135–350)* | 272 (157–369)* | 184 (113–236)* | 334 (238–431) |
| Prothrombin time (%) | 71 (61–82)* | 73 (61–86)* | 66 (61–75)* | 90 (80–95) | 81 (70–98)* | 84 (72–102)* | 65 (50–80)* | 102 (92–112) | 88 (74–99)* | 88 (76–101)* | 84 (64–96)* | 99 (89–113) |
| APACHE II | 32 (26–36)* | 30 (25–35)* | 36 (28–42)* | 9 (7–12) | ||||||||
| SOFA | 13 (11–15)* | 12 (10–14)* | 15 (12–16)* | 2 (0–4) | 11 (9–14)* | 10 (8–13)* | 13 (11–17)* | 1 (0–2) | 9 (3–12)* | 7 (3–11)* | 13 (9–17)* | 0 (0–0) |
*p < 0.05 versus CG.
APACHE, acute physiology and chronic health evaluation; PCT, procalcitonin; SOFA, sepsis-related organ failure assessment; CG, control group.