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. 2018 Jun 25;9:1448. doi: 10.3389/fimmu.2018.01448

Table 1.

Laboratory parameters and results of APACHE II-, and SOFA scores at inclusion, after 3, and 7 days in the septic- (SG, n = 51), septic survived- (SSG, n = 39), septic non-survived- (SNSG, n = 12), and CG (n = 48); (median/0.25–0.75 quartile).

Values At inclusion
After 3 days
After 7 days
Sepsis group (n = 51)
CG (n = 48) Sepsis group (n = 51)
CG (n = 48) Sepsis group (n = 51)
CG (n = 48)
SG (all) SSG SNSG SG (all) SSG SNSG SG (all) SSG SNSG
Lactate (mmol/l) 1.7 (1.5–2.9)* 1.7 (1.5–2.5)* 2.4 (1.4–5.3)* 1.1 (0.9–1.3) 1.7 (1.2–2.4)* 1.6 (1.2–2.2)* 1.9 (1.8–3.4)* 1.3 (0.9–1.6) 1.4 (1.2–2.1) 1.4 (1.1–2.0) 2.2 (1.4–3.2) 1.6 (1.3–2.8)
Bilirubin (μmol/l) 19.9 (12.1–36.8)* 19.2 (13.9–37.1)* 21.4 (11.7–33) 15.2 (11.3–18.8) 15.7 (10.7–30.9)* 15.0 (10.8–30.0)* 21.5 (10.0–35.9)* 11.0 (8.6–15.7) 13.4 (9.1–24.3)* 11.9 (8.6–23.9)* 16.8 (12.3–27.8)* 9.1 (7.6–10.8)
Ammonia (mmol/l) 51.3 (34.5–63.9)* 43.1 (30.9–60.4)* 54.4 (43.0–68.7)* 31.7 (22.4–39.4) 49.3 (38.4–65.4)* 48.1 (38.7–60.2)* 50.4 (35.5–78.8)* 31.8 (25.5–38.7) 43.7 (37.3–59.2)* 43.6 (36.8–59.8)* 48.4 (38.3–80.2)* 32.4 (24.0–43.5)
Creatinine (μmol/l) 136 (94–202)* 130 (93–193)* 161 (103–245)* 78 (66–94) 130 (92–215)* 127 (92–190)* 148 (108–232)* 77 (65–88) 83 (64–165)* 82 (62–155) 95 (82–249)* 79 (65–89)
Urea (mmol/l) 10.5 (7.3–17.4)* 9.4 (7.3–14.5)* 17.3 (7.7–22.7)* 4.4 (3.4–5.8) 12.2 (7.9–18.1)* 10.8 (7.0–15.1)* 18 (11.4–26.7)* 4.6 (3.3–5.5) 11.3 (6.3–19.7)* 11 (6.1–16.2)* 18.6 (8.2–35.0)* 4.5 (3.6–5.4)
PCT (ng/ml) 12.2 (3.9–32.5)* 10.5 (3.3–28.8)* 18.2 (4.4–47.2)* 0.5 (0.2–0.8) 5.0 (2.0–15.7)* 4.6 (2.0–12.5)* 6.9 (2.2–24.0)* 0.4 (0.1–0.6) 0.7 (0.4–3.3)* 0.7 (0.4–2.2)* 4.6 (0.4–6.7)* 0.2 (0.1–0.2)
Leukocytes (GpT/l) 14.8 (9.1–23.0)* 14.6 (8.2–22.1)* 20.2 (11.8–51.5)* 9.1 (7.6–11.7) 12.6 (8.6–16.7)* 11.6 (8.3–15.4)* 14.6 (10.5–24.4)* 8.9 (7.3–11.5) 13.3 (11.0–18.3)* 13.2 (10.4–17.7)* 15.3 (12.4–25.3)* 9.0 (8.0–10.9)
Thrombocytes (GpT/l) 191 (106–254) 201 (107–254) 174 (65–248) 184 (136–238) 170 (100–244) 187 (109–256) 149 (71–189)* 187 (149–252) 229 (135–350)* 272 (157–369)* 184 (113–236)* 334 (238–431)
Prothrombin time (%) 71 (61–82)* 73 (61–86)* 66 (61–75)* 90 (80–95) 81 (70–98)* 84 (72–102)* 65 (50–80)* 102 (92–112) 88 (74–99)* 88 (76–101)* 84 (64–96)* 99 (89–113)
APACHE II 32 (26–36)* 30 (25–35)* 36 (28–42)* 9 (7–12)
SOFA 13 (11–15)* 12 (10–14)* 15 (12–16)* 2 (0–4) 11 (9–14)* 10 (8–13)* 13 (11–17)* 1 (0–2) 9 (3–12)* 7 (3–11)* 13 (9–17)* 0 (0–0)

*p < 0.05 versus CG.

APACHE, acute physiology and chronic health evaluation; PCT, procalcitonin; SOFA, sepsis-related organ failure assessment; CG, control group.