Table 3.
Cytokines values at inclusion, and after 3 days in the septic- (SG, n = 51), septic survived- (SSG, n = 39), septic none survived- (SNSG, n = 12), and CG (n = 48); (median/0.25–0.75 quartile).
| Cytokine (pg/ml) | At inclusion |
After 3 days |
||||||
|---|---|---|---|---|---|---|---|---|
| Sepsis group (n = 51) |
CG (n = 48) | Sepsis group (n = 51) |
CG (n = 48) | |||||
| SG (all) | SSG | SNSG | SG (all) | SSG | SNSG | |||
| IL-1 beta | 3.9 (2.4–4.5) | 5.8 (2.5–6.5) | 2.7 (2.5–2.9) | 2.5 (2.4–2.6) | 2.5 (2.3–2.6) | 2.6 (2.4–2.8) | 2.4 (2.2–2.9) | 2.6 (2.5–2.7) |
| IL-6 | 268 (106–557.5)+,° | 268 (116.5–557.5)#,° | 226 (98–501.5)§,° | 78 (42.1–143)° | 45.3 (25.9–90.5) | 48.2 (27–89) | 42.3 (25.4–155.9) | 30.5 (22.1–58) |
| IL-10 | 11.1 (2.4–25.9)+ | 12.3 (3.8–24.1)#,° | 4.6 (2.5–33.3) | 2.5 (2.3–8.6) | 7.5 (2.4–12)+ | 7.2 (2.3–11.9)# | 7.9 (2.5–17.5)§ | 2.5 (2.2–2.6) |
| TNF-alpha | 20.4 (12.9–32.2)+,° | 20.4 (13.9–29.8)#,° | 20.7 (11.2–41.9)§,° | 7.7 (5.7–9.7) | 14.7 (10.2–19.9)+ | 15.5 (11.2–19.9)# | 10.8 (7.1–23.2) | 6.6 (5.6–9.7) |
Statistically significant (p < 0.05): #between SSG and CG (U-test); §between SNSG and CG (U-test); +between SG and CG; °between inclusion and day 3.
IL, interleukin; TNF, tumor necrosis factor; CG, control group.