Figure 1.

DLG-1 is a MAGUK protein most similar to SAP97. (A) Deduced amino acid sequence of DLG-1 with PDZ domains in blue, SH3 domain in red, and guanylate kinase domain in gray. (B) Alignment of the amino-terminal 99 amino acids of DLG-1 with SAP97. Identical residues are indicated in black, whereas conserved residues are indicated in gray. (C) Schematic diagrams of the DLG-1:: GFP chimeric proteins. Embryos expressing DLG-1:: GFP (green) in intestine (D) and hypodermis (E) are shown with DAPI-stained nuclei (blue). Adult worms express DLG-1:: GFP in the Pnp epithelial cells (F) and lateral seam cells (G). Scale bar represents 10 μm.