Table 1. Values of ΔG° and m for the Cooperative and Isodesmic Pathways, Obtained from the Global Fitting of UV and CD Data for the Various Concentrations of (S)-1.
1 μM | 10 μM | 100 μM | |
---|---|---|---|
ΔG°coop (kJ/mol) | –46 | –45 | –33 |
mcoop (kJ/mol) | 194 | 101 | 67 |
σa | 7.3 × 10–3 | 2.3 × 10–3 | 6.7 × 10–4 |
ΔG°iso (kJ/mol) | –40 | –41 | –31 |
miso (kJ/mol) | 91 | 56 | 41 |
The cooperativity parameter σ is determined at 293 K.28