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. 2018 May 16;12(7):1012–1025. doi: 10.1002/1878-0261.12203

Figure 6.

Figure 6

Distant relapse‐free survival of breast cancer patients according to p‐Akt and/or Vav1 status of their primary tumors. (A) Kaplan–Meier estimates of distant relapse‐free survival (DRFS) in patients (n = 126) according to p‐Akt status. (B) Kaplan–Meier estimates of DRFS in patients with p‐Akthigh tumors (n = 38) (left panel), and in patients with p‐Aktlow tumors (n = 88) (right panel), according to high (green solid line) and low (blue dashed line) expression of Vav1. In these cohort of patients, a distant relapse occurred in the 11% (10/88) p‐Aktlow and 13% (5/38) p‐Akthigh tumors, in the 16% (4/25) Vav1low and 8% (1/13) Vav1high of patients with p‐Akthigh tumors, and in the 23% (8/35) Vav1low and 4% (2/53) Vav1high of patients with p‐Aktlow tumors.