Table 5.
Vav1 status according to clinicopathological features of breast cancer patients with p‐Aktlow tumors (n = 88)
| Variable | Vav1 | P a | |
|---|---|---|---|
| Low, n (%) | High, n (%) | ||
| Age at diagnosis (years) | |||
| <50 | 15 (42.9) | 10 (18.9) | 0.018 |
| 50–65 | 9 (25.7) | 28 (52.8) | |
| >65 | 11 (31.4) | 15 (28.3) | |
| Menopausal status | |||
| Pre/perimenopausal | 15 (42.9) | 12 (22.6) | 0.054 |
| Postmenopausal | 20 (57.1) | 41 (77.4) | |
| Tumor size | |||
| ≤2 cm | 25 (71.4) | 35 (66.0) | 0.646 |
| >2 cm | 10 (28.6) | 18 (34.0) | |
| Histotypes | |||
| Ductal carcinoma | 27 (77.1) | 46 (86.8) | 0.466 |
| Lobular carcinoma | 5 (14.3) | 5 (9.4) | |
| Other | 3 (8.6) | 2 (3.8) | |
| Molecular subtypes | |||
| Luminal A‐like | 18 (51.4) | 23 (43.4) | 0.260 |
| Luminal B‐like (HER2 negative) | 6 (17.1) | 15 (28.3) | |
| Luminal B‐like (HER2 positive) | 1 (2.9) | 4 (7.5) | |
| HER2 positive (nonluminal) | 2 (5.7) | 0 (0.0) | |
| Triple negative (ductal) | 8 (22.9) | 11(20.8) | |
| Tumor grade | |||
| 1 | 6 (17.1) | 6 (11.3) | 0.478 |
| 2 | 16 (45.8) | 31 (58.5) | |
| 3 | 13 (37.1) | 16 (30.2) | |
| Ki‐67 | |||
| Low | 22 (62.9) | 31 (58.5) | 0.824 |
| High | 13 (37.1) | 22 (41.5) | |
a
Pearson's chi‐square test.