Table 2.
Crude and adjusteda odds ratios (ORs) and mean differences in characteristics at birth and present for participants with polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) or both compared with healthy controls (n = 1941).
Characteristic | OR/mean difference (95% CI) | |||||
---|---|---|---|---|---|---|
GDM + PCOS (n = 105) | GDM + non-PCOS (n = 909) | Non-GDM + PCOS (n = 69) | ||||
Crude | Adjusteda | Crude | Adjusteda | Crude | Adjusteda | |
Participants’ birthb | ||||||
Birth weight (g) | −147 (−255 to −40) | −181 (−299 to −64) | −79 (−131 to −27) | −117 (−174 to −60) | 41 (−90 to 172) | 47 (−84 to 179) |
s.d. score for birth weight | −0.37 (−0.61 to −0.14) | −0.40 (−0.67 to −0.14) | −0.14 (−0.25 to −0.04) | −0.23 (−0.35 to −0.10) | 0.03 (−0.26 to 0.31) | 0.06 (−0.22 to 0.34) |
Gestational age (weeks) | −0.1 (−0.5 to 0.3) | −0.2 (−0.6 to 0.3) | −0.2 (−0.4 to 0.05) | −0.2 (−0.5 to −0.01) | 0.5 (0.03–1.0) | 0.5 (0.01–0.9) |
<37 + 0 weeks | 1.43 (0.48–4.22) | 1.47 (0.43–4.99) | 2.00 (1.20–3.33) | 2.24 (1.28–3.92) | ||
SGAc | 3.42 (1.29–9.07) | 4.08 (1.30–12.6) | 1.56 (0.81–3.00) | 1.66 (0.81–3.44) | 0.84 (0.11–6.44) | 0.99 (0.13–7.78) |
Participants’ current characteristics | ||||||
Age at delivery (years) | 3.2 (2.2–4.2) | 2.5 (1.6–3.4) | 2.7 (2.2–3.2) | 2.2 (1.8–2.7) | 1.1 (−0.1 to 2.3) | 0.9 (−0.1 to 1.9) |
Height (cm) | −0.5 (−1.6 to 0.7) | −0.9 (−2.2 to 0.4) | −0.6 (−1.1 to −0.1) | −0.9 (−1.5 to −0.3) | 0.9 (−0.5 to 2.4) | 0.6 (−0.8 to 2.1) |
Weight (kg) | 16.1 (13.4–18.8) | 15.2 (12.4–17.9) | 11.2 (9.8–12.6) | 9.9 (8.4–11.3) | 3.2 (0.1–6.2) | 3.1 (0.0–6.1) |
Pre-pregnancy BMI (kg/m2) | 6.1 (5.2–7.0) | 5.8 (4.8–6.7) | 4.3 (3.8–4.8) | 3.9 (3.4–4.4) | 0.9 (−0.1 to 1.9) | 1.0 (−0.1 to 2.0) |
aLinear regression for continuous variables and logistic regression for categorical variables adjusted for participants’ parity, smoking during pregnancy, educational attainment, delivery hospital, age and pre-pregnancy BMI; bas reported by the participants at recruitment in this study; csmall for gestational age (<−2 s.d.).
GDM, gestational diabetes mellitus; PCOS, polycystic ovary syndrome; s.d., standard deviation.