. 2018 May 30;238(2):129–136. doi: 10.1530/JOE-18-0183
This work is licensed under a Table 1.
Body and skeletal characteristics of 16-week-old sham-operated Lck-ERα−/− and control mice.
| Control | Lck-ERα−/− | |
|---|---|---|
| Body weight (g) | 21.8 ± 0.5 | 22.8 ± 0.7 |
| Uterus weight/bw (mg/g) | 2.9 ± 0.3 | 3.2 ± 0.3 |
| Thymus weight/bw (mg/g) | 2.5 ± 0.1 | 2.6 ± 0.1 |
| Total body aBMD (mg/cm2) | 49.8 ± 0.5 | 49.2 ± 0.4 |
| Lumbar spine aBMD (mg/cm2) | 56.8 ± 1.4 | 56.3 ±1.0 |
| Vertebra, L5 | ||
| Bone volume/total volume (BV/TV; %) | 22.9 ± 0.7 | 24.5 ± 0.6 |
| Trabecular number (Tb.N; 1/mm) | 4.9 ± 0.1 | 5.3 ± 0.1 |
| Trabecular thickness (Tb.Th; μm) | 46.4 ± 0.8 | 46.5 ± 0.6 |
| Trabecular separation (Tb.Sp; μm) | 152 ± 2.5 | 147 ± 3.4 |
| Femur | ||
| Bone volume/total volume (BV/TV; %) | 14.7 ± 0.8 | 16.1 ± 0.8 |
| Trabecular number (Tb.N; 1/mm) | 3.3 ± 0.2 | 3.6 ± 0.2 |
| Trabecular thickness (Tb.Th; μm) | 44.6 ± 1.0 | 45.0 ± 1.3 |
| Trabecular separation (Tb.Sp; μm) | 118 ± 2.0 | 116 ± 2.0 |
| Cortical thickness (Ct.Th; μm) | 186 ± 2.5 | 188 ± 3.0 |
| Endosteal circumference (Endo. C; mm) | 3.40 ± 0.04 | 3.32 ± 0.04 |
| Periosteal circumference (Peri. C; mm) | 4.57 ± 0.04 | 4.50 ± 0.05 |
| Serum biomarkers | ||
| P1NP (ng/mL) | 73.6 ± 4.4 | 85.7 ± 5.7 |
| CTX-I (ng/mL) | 16.2 ± 1.9 | 17.8 ± 2.3 |
Values are given as mean ± s.e.m. (n = 9–10). Student’s t test, Lck-ERα−/− vs controls.
CTX-I, C-terminal type I collagen fragments; P1NP, procollagen type I N propeptide.