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. 2018 Jun 19;9(6):305. doi: 10.3390/genes9060305

Figure 3.

Figure 3

MiRAR–let-7 with KRas-3-UTR is let-7 specific. Fluorescence intensities (a) and cell images (b) for HEK 293 cells co-transfected with pMiRAR-let-7 and tdTomato. HEK 293 cells were grown to confluence and treated as outlined. Cells were either transfected with the original pMiRAR-let-7 construct (Wild Type (WT)-KRas) or a construct containing mutated let-7 binding sites (pMiRAR-let-7-mutant). Error bars are based on three biological replicates and show one standard deviation. White bars represent 200 µm. p values are *** < 0.001.