Table 1.
Demographic and cognitive variables by Aβ status in test dataset.
| No. Aβ-/Aβ+ | Aβ- | Aβ+ | p-value | |
|---|---|---|---|---|
| DEMOGRAPHICS | ||||
| Age, years | 677/230 | 66.7 (14.7) | 71.8 (8.6) | < 0.001 |
| Female, n | 677/230 | 358 (53%) | 128 (56%) | 0.466 |
| Education, years | 677/230 | 14.7 (3.7) | 14.7 (3.6) | 0.907 |
| APOE-ε4 carrier, n | 629/218 | 174 (28%) | 105 (48%) | < 0.001 |
| MMSE, score | 677/230 | 29.0 (1.1) | 28.9 (1.1) | 0.637 |
| Abnormal CSF t-tau, n | 398/175 | 42 (11%) | 45 (26%) | < 0.001 |
| Abnormal CSF p-tau, n | 395/174 | 100 (25%) | 85 (49%) | < 0.001 |
| COGNITIVE RAW SCORES | ||||
| AVLT Immediate, words recalled | 440/183 | 45.5 (10.1) | 43.5 (9.4) | 0.020 |
| AVLT Delayed, words recalled | 439/182 | 8.8 (3.4) | 7.7 (3.6) | < 0.001 |
| VFT, words named | 526/190 | 21.6 (5.7) | 20.9 (5.5) | 0.178 |
| TMT-A, seconds | 674/230 | 36.7 (14.6) | 39.8 (17.7) | 0.011 |
| TMT-B, seconds | 670/228 | 85.5 (38.3) | 99.6 (62.1) | < 0.001 |
Results are mean (SD) or frequency (%): Aβ, amyloid-beta; APOE, Apolipoprotein E; AVLT, Auditory Verbal Learning Test; CSF, cerebrospinal fluid; MMSE, mini mental state examination; No, number; p-tau, phosphorylated tau; TMT, trail making test; t-tau, total tau; VFT, verbal fluency test.