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. 2018 Jun 25;10:193. doi: 10.3389/fnagi.2018.00193

Table 6.

Predictive accuracy of progression to dementia within 2 years given an abnormal performance using Aβ- or published norms.

Test Norms n Normal/abnormal OR Sensitivity Specificity PPV NPV
AVLT Immediate Aβ- norms 406/664 4.72 (2.9–7.8) 0.87 (0.8–0.9) 0.42 (0.4–0.5) 0.19 (0.2–0.22) 0.95 (0.9–0.97)
Published norms 790/280 3.45 (2.4–5.0) 0.50 (0.4–0.6) 0.78 (0.7–0.8) 0.26 (0.2–0.3) 0.91 (0.9–0.93)
AVLT Delayed Aβ- norms 570/500 4.26 (2.8–6.4) 0.76 (0.7–0.8) 0.58 (0.5–0.6) 0.22 (0.2–0.3) 0.94 (0.9–0.96)
Published norms 735/335 6.43 (4.4–9.4) 0.69 (0.6–0.8) 0.75 (0.7–0.8) 0.30 (0.2–0.3) 0.94 (0.9–0.95)
TMT-A Aβ- norms 306/427 1.78 (1.1–2.9) 0.70 (0.6–0.8) 0.43 (0.4–0.5) 0.15 (0.1–0.2) 0.91 (0.9–0.94)
Published norms 582/145 1.38 (0.8–2.3) 0.25 (0.2–0.3) 0.81 (0.8–0.84) 0.16 (0.1–0.2) 0.88 (0.85–0.9)
TMT-B Aβ- norms 423/237 2.83 (1.8–4.5) 0.58 (0.5–0.7) 0.67 (0.6–0.7) 0.20 (0.1–0.3) 0.92 (0.9–0.95)
Published norms 539/155 1.84 (1.1–3.0) 0.33 (0.2–0.4) 0.79 (0.76–0.8) 0.19 (0.1–0.2) 0.89 (0.86–0.9)

Numbers are estimates with (95% CI): Aβ, amyloid-beta; AVLT, Auditory Verbal Learning Test; NPV, negative predictive value; OR, odds ratio; PPV, positive predictive value; TMT-A, Trail Making Test part A; TMT-B, Trail Making Test part B.