Table 6.
Test | Norms | n Normal/abnormal | OR | Sensitivity | Specificity | PPV | NPV |
---|---|---|---|---|---|---|---|
AVLT Immediate | Aβ- norms | 406/664 | 4.72 (2.9–7.8) | 0.87 (0.8–0.9) | 0.42 (0.4–0.5) | 0.19 (0.2–0.22) | 0.95 (0.9–0.97) |
Published norms | 790/280 | 3.45 (2.4–5.0) | 0.50 (0.4–0.6) | 0.78 (0.7–0.8) | 0.26 (0.2–0.3) | 0.91 (0.9–0.93) | |
AVLT Delayed | Aβ- norms | 570/500 | 4.26 (2.8–6.4) | 0.76 (0.7–0.8) | 0.58 (0.5–0.6) | 0.22 (0.2–0.3) | 0.94 (0.9–0.96) |
Published norms | 735/335 | 6.43 (4.4–9.4) | 0.69 (0.6–0.8) | 0.75 (0.7–0.8) | 0.30 (0.2–0.3) | 0.94 (0.9–0.95) | |
TMT-A | Aβ- norms | 306/427 | 1.78 (1.1–2.9) | 0.70 (0.6–0.8) | 0.43 (0.4–0.5) | 0.15 (0.1–0.2) | 0.91 (0.9–0.94) |
Published norms | 582/145 | 1.38 (0.8–2.3) | 0.25 (0.2–0.3) | 0.81 (0.8–0.84) | 0.16 (0.1–0.2) | 0.88 (0.85–0.9) | |
TMT-B | Aβ- norms | 423/237 | 2.83 (1.8–4.5) | 0.58 (0.5–0.7) | 0.67 (0.6–0.7) | 0.20 (0.1–0.3) | 0.92 (0.9–0.95) |
Published norms | 539/155 | 1.84 (1.1–3.0) | 0.33 (0.2–0.4) | 0.79 (0.76–0.8) | 0.19 (0.1–0.2) | 0.89 (0.86–0.9) |
Numbers are estimates with (95% CI): Aβ, amyloid-beta; AVLT, Auditory Verbal Learning Test; NPV, negative predictive value; OR, odds ratio; PPV, positive predictive value; TMT-A, Trail Making Test part A; TMT-B, Trail Making Test part B.