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. 2018 Jun 7;9(6):289. doi: 10.3390/genes9060289

Figure 2.

Figure 2

Insights into heart regeneration gained from NGS-based studies. Different approaches for cardiac injury induction in adult zebrafish (upper) and neonatal and adult mouse used to investigate heart regeneration. NGS studies on cardiac repair in lower vertebrates (zebrafish) and mammals (mouse) have identified molecular regulators including driving genes, enhancers, miRNA, as well as cellular and environmental factors directing efficient heart regeneration [73,74,75,76,77,78,79,80].