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. 2018 Jun 2;8(6):399. doi: 10.3390/nano8060399

Figure 7.

Figure 7

(A) Graphical representation of the effect of rh RANKL concentration and time in culture on osteoclastogenesis. (B) The effect of peptides on osteoclastogenesis after a four-day culture with (i) no cytokines or peptides, (ii) rh RANKL only, (iii) rh M-CSF only, (iv) rh RANKL and rh M-CSF, (v) OP3-4, (vi) DOTA-OP3-4, (vii) DOTA-Gd-OP3-4, and (viii) rh OPG (positive control): iv–ix had rh RANKL (50 ng/mL) and rh M-CSF (25 ng/mL). (C) Graphical representation of osteoclastogenesis inhibition by OPG mimetic peptides.