Table 1.
Altogether, 14 significant regulons that are verified and mapped to known transcription factors (TFs). According to analyses, operon numbers and DEG determination (yes or no), matched template TFs and mapped TFs were assigned for each significant regulon, respectively, and were aligned based on regulon ID number. Five regulons containing DEGs and having the corresponding TF at the same time were bolded, being computationally verified as the regulons responsible for acid stress in MG1363.
| Regulon ID | No. of Operons | DEG | TF Template | TF (Gene) BLAST in MG1363 |
|---|---|---|---|---|
| Regulon #2 | 82 | Y | spo0A | llrC (llmg_0414) |
| Regulon #3 | 32 | Y | FoxQ1 | N/A |
| Regulon #4 | 20 | Y | SPT2 | N/A |
| Regulon #7 | 49 | Y | lhfB | hllA (llmg_0496) |
| Regulon #10 | 5 | N | GAL80 | llmg_0271 |
| Regulon #12 | 259 | Y | CovR | llrA (llmg_0908) |
| Regulon #15 | 19 | Y | c4494 | ccpA (llmg_0775) |
| Regulon #20 | 79 | Y | NHP6A | N/A |
| Regulon #28 | 5 | Y | 1Z916 | N/A |
| Regulon #31 | 65 | Y | ihfA | hllA (llmg_0496) |
| Regulon #37 | 10 | N | CovR | llrA (llmg_0908) |
| Regulon #40 | 7 | Y | Awh | N/A |
| Regulon #44 | 12 | N | YBR182C | N/A |
| Regulon #47 | 5 | N | RHE_PF00288 | ccpA (llmg_0775) |
Abbreviations: N, no; Y, yes; N/A, not found.