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. 2018 May 18;6(2):44. doi: 10.3390/microorganisms6020044

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Binding of TFF1 dimer to gastric and colonic mucins. Mucin microarrays containing human gastric (GM) and colonic mucins (CM) were incubated with TFF1 dimer (20 µg/mL). GM = gastric mucin, CM = colonic mucin, UCM = ulcerative colitis mucin. GM4 was not printed on these microarrays. Results are presented as the mean of three experimental replicates ± one standard deviation, with the binding intensity indicated by the relative fluorescence intensity. The level of TFF1 binding to gastric mucins was significantly higher than TFF1 binding to colonic mucins (p < 0.0001, Mann-Whitney U test).