. Author manuscript; available in PMC: 2018 Jul 2.

Published in final edited form as: N Engl J Med. 2012 Mar 15;366(11):981–990. doi: 10.1056/NEJMoa1113135

Table 3.

Mortality from Prostate Cancer among Men 55 to 69 Years of Age, According to Study Period

	Intervention			Control			Rate Ratio¹ (95% CI)	Rate difference per 1000 persons year (95% CI)	Rate difference per 1000 men

	Prostate Cancer deaths N	Person years	Rate per 1000 person years	Prostate Cancer deaths N	Person years	Rate per 1000 person years

Years 1-9	189	608852	0.31	274	745912	0.37	0.85 (0.71 – 1.03) P=0.09	-0.06 (-0.12 – +0.005)	-0.47
Years 1-9	189	608852	0.31	274	745912	0.37	0.85 (0.71 – 1.03) P=0.09	-.0.06 (-0.12 – + 0.000009)^*	-0.46^*

Years 8-9	71	122867	0.58	118	151319	0.78	0.74 (0.55-0.99) P = 0.04	-0.20 (-0.40 – -0.000007)	-0.35
Years 8-9	71	122867	0.58	118	151319	0.78	0.74 (0.55-0.99) P = 0.04	-0.20 (-0.40 – + 0.00001)^*	-0.33^*

Years 10-11	56	97994	0.57	111	120900	0.92	0.62 (0.45 – 0.85) P=0.003	-0.35 (-0.57 – -0.12)	-0.47
Years 10-11	56	97994	0.57	111	120900	0.92	0.62 (0.45 – 0.85) P=0.003	-0.37 (-0.61 – -0.12)^*	-0.48^*

Year 1-11	245	706846	0.35	385	866812	0.44	0.79 (0.67-0.92) P = 0.003	-0.10 (-0.16 – -0.04)	-0.95
Year 1-11	245	706846	0.35	385	866812	0.44	0.79 (0.67-0.92) P = 0.003	-0.10 (-0.17 – -0.03)^*	-0.94^*

Years 12+	54	57387	0.94	77	66241	1.16	0.80 (0.56 – 1.13) P=0.21	-0.22 (-0.58 – +0.14)	-0.12
Years 12+	54	57387	0.94	77	66241	1.16	0.80 (0.56 – 1.13) P=0.21	-0.26 (-0.64 – + 0.12)^*	-0.19^*

Total	299	764233	0.39	462	933052	0.50	0.79 (0.68 – 0.91) P=0.001	-0.10 (-0.17 – -0.04)	-1.07
Total	299	764233	0.39	462	933052	0.50	0.79 (0.68 – 0.91) P=0.001	-0.11 (-0.18 – 0.04)^*	-1.13^*

Adjusted by centre

Finland control population weighted by 2/3