Figure 4.

The intranuclear distribution of centromeric α-satellite DNA correlates with chromosome banding pattern. Observed distribution frequencies are plotted against frequencies predicted by multiple regression with variables B₃₄ and B_NOR. LamTot refers to the totality of α-satellite signals adjacent to the lamina, NucTot represents the totality of α-satellite signals in the vicinity of the nucleolus, and Non includes signals that do not associate with either the lamina or the nucleolus. If the model would fit the data perfectly, all the points would be over the line with unitary slope and zero origin. Possible reasons to explain the discrepancies observed for centromeres on chromosomes 1, 9,and 17 are discussed in the text. Note that predicted frequencies were transformed back to the original scale using

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