Table 2.
Relationship of QRS duration with incident atrial fibrillation
Events/No. at risk | Person-years | Incidence rate Per 1000 person-years (95%CI) |
Model 1* HR (95%CI) |
P-value | Model 2† HR (95%CI) |
P-value | |
---|---|---|---|---|---|---|---|
QRS, <100 ms | 1,457/11,898 | 224,657 | 6.5 (6.2, 6.8) | Ref | - | Ref | - |
QRS, 100–119 ms | 497/2,990 | 53,764 | 9.2 (8.5, 10.1) | 1.26 (1.13, 1.40) | <0.001 | 1.13 (1.02, 1.26) | 0.03 |
QRS, ≥120 ms | 87/426 | 6,628 | 13.1 (10.6, 16.2) | 1.60 (1.28, 1.99) | <0.001 | 1.35 (1.08, 1.68) | 0.008 |
P for trend <0.001 | P for trend 0.002 | ||||||
QRS per 1-SD increase‡ | 2,041/15,314 | 285,050 | 7.2 (6.9, 7.5) | 1.11 (1.07, 1.15) | <0.001 | 1.05 (1.01, 1.10) | 0.01 |
Adjusted for age, sex, race, and study site.
Adjusted for Model 1 covariates plus body mass index, systolic blood pressure, smoking, diabetes, heart rate, coronary heart disease, and heart failure.
CI=confidence interval; HR=hazard ratio; Ref= Reference.
1 standard deviation = 12ms.