Table 2.

Mean particle size and polydispersity index (PDI) for propranolol hydrochloride formulations (mean ± SD, n = 5).

Formulation No.	State in Full Factorial Design	Particle Size (nm)	PDI
1	+++	385 ± 30	0.44 ± 0.04
2	−++	491 ± 51	0.51 ± 0.03
3	+−+	554 ± 29	0.29 ± 0.018
4	+−−	840 ± 33	0.38 ± 0.035
5	−+−	462 ± 28	0.5 ± 0.025
6	−−+	686 ± 56	0.56 ± 0.011
7	++−	706 ± 19	0.22 ± 0.02
8	−−−	880 ± 66	0.4 ± 0.03