Table 5.
Adjusted HRs and 95% CIs for cancer-specific survival by stage in different age groups
| 20–39 years: analysis type | All stages (N=2105)
|
Stage I (N=336)
|
Stage II (N=702)
|
Stage III (N=1067)
|
||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| Unadjusted | ||||||||
| RCC | 1 | 0.91 | 1 | 0.40 | 1 | 0.001 | 1 | 0.17 |
| LCC | 1.01 (0.84–1.22) | 0.62 (0.21–1.85) | 2.19 (1.40–3.44) | 0.86 (0.70–1.07) | ||||
| Adjusted* | ||||||||
| RCC | 1 | 0.29 | 1 | 0.92 | 1 | 0.02 | 1 | 0.92 |
| LCC | 1.12 (0.91–1.37) | 1.06 (0.29–3.91) | 1.82 (1.12–2.97) | 0.99 (0.79–1.24) | ||||
|
| ||||||||
| 40–49 years: analysis type |
All stages (N=6092)
|
Stage I (N=1363)
|
Stage II (N=2024)
|
Stage III (N=2705)
|
||||
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
|
| ||||||||
| Unadjusted | ||||||||
| RCC | 1 | <0.001 | 1 | 0.46 | 1 | 0.17 | 1 | <0.001 |
| LCC | 0.81 (0.73–0.91) | 1.277 (0.67–2.45) | 1.17 (0.93–1.47) | 0.78 (0.68–0.89) | ||||
| Adjusted* | ||||||||
| RCC | 1 | 0.11 | 1 | 0.10 | 1 | 0.49 | 1 | 0.008 |
| LCC | 0.91 (0.81–1.02) | 1.796 (0.90–3.57) | 1.09 (0.86–1.38) | 0.83 (0.72–0.95) | ||||
Note:
*
Cox regression model controlling for year of diagnosis, age groups, sex, race, histological subtype, tumor grade, AJCC TNM stage, the number of LNs examined, and marriage status.
Abbreviations: HR, hazard ratio; CI, confidence interval; RCC, right-sided colon cancer; LCC, left-sided colon cancer; AJCC, American Joint Committee on Cancer; LNs, lymph nodes.