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. Author manuscript; available in PMC: 2018 Jul 2.
Published in final edited form as: Am J Med Genet A. 2015 Jul 2;167A(11):2533–2540. doi: 10.1002/ajmg.a.37214

FIG. 1.

FIG. 1

Mutations in a conserved C-terminal helical domain of Orc6 used in this study. Black box represents DNA binding N-terminal domain of Orc6. Conservatives amino acids of the C-terminus are shown in insert. Mutated amino acids are colored in red. Arrow indicates Meier-Gorlin syndrome associated mutation.