. 2001 Nov;12(11):3589–3600. doi: 10.1091/mbc.12.11.3589

Table 2.

Phenotypes of homozygous and heteroallelic diploids

	Wild type	Glu12Gly	Val21Glu	Ala55Thr	Ile59Asn	Glu89Lys	Phe116Leu	Leu137Ile	Phe202Tyr	Ile221Thr	cdc28-1N
Wild type	⁺/−	⁺	⁺	⁺	⁺	⁺	⁺	⁺	⁺	⁺	⁺
	1.44	1.56	1.61	1.65	1.63	1.61	1.55	1.39	1.49	1.53	1.6
Glu12Gly	⁺	⁺⁺⁺⁺	⁺	⁺⁺	⁺⁺	⁺⁺	⁺	⁺⁺	⁺	⁺⁺	⁺
	1.62	2.62	1.62	1.83	1.81	1.71	1.63	1.76	1.64	1.61	1.71
Val21Glu	⁺	⁺⁺	⁺⁺⁺⁺	⁺⁺	⁺⁺	⁺⁺	⁺⁺	⁺	⁺⁺	⁺⁺	⁺
	1.48	1.89	2.64	1.75	1.75	1.73	1.74	1.56	1.80	1.91	1.76
Ala55Thr	⁺	⁺⁺⁺	⁺⁺	⁺⁺⁺⁺	⁺⁺⁺⁺	⁺⁺	⁺	⁺⁺	⁺⁺	⁺	⁺⁺
	1.64	1.99	1.78	2.65	2.66	1.90	1.66	1.86	1.80	1.71	1.91
Ile59Asn	⁺	⁺	⁺⁺	⁺⁺⁺⁺	⁺⁺⁺⁺	⁺	⁺	⁺⁺	⁺⁺	⁺⁺	⁺⁺
	1.61	1.73	1.99	2.60	2.66	1.68	1.63	1.81	1.81	1.89	1.83
Glu89Lys	⁺	⁺	⁺	⁺⁺	⁺	⁺⁺⁺⁺	⁺⁺	⁺	⁺⁺	⁺⁺	⁺
	1.63	1.69	1.59	1.83	1.66	2.64	1.83	1.69	1.86	1.73	1.73
Phe116Leu	⁺	⁺	⁺⁺	⁺	⁺	⁺⁺	⁺⁺⁺⁺	⁺	⁺	⁺⁺	⁺
	1.51	1.71	1.86	1.71	1.69	1.84	2.69	1.69	1.61	1.81	1.62
Leu137Ile	⁺	⁺⁺	⁺⁺	⁺⁺	⁺⁺	⁺⁺	⁺	⁺⁺⁺⁺	⁺	⁺⁺	⁺
	1.44	1.72	1.76	1.79	1.83	1.83	1.63	2.71	1.56	1.81	1.56
Phe202Tyr	⁺	⁺⁺	⁺	⁺	⁺	⁺	⁺	⁺⁺	⁺⁺⁺⁺	⁺⁺	⁺⁺
	1.56	1.88	1.65	1.68	1.69	1.69	1.61	1.87	2.59	1.88	1.83
Ile221Thr	⁺	⁺	⁺⁺	⁺⁺	⁺⁺	⁺⁺	⁺	⁺⁺	⁺⁺	⁺⁺⁺⁺	⁺
	1.56	1.61	1.72	1.83	1.81	1.79	1.67	1.87	1.87	2.66	1.65
cdc28-1N	⁺	⁺⁺	⁺	⁺⁺	⁺⁺	⁺⁺	⁺⁺	⁺	⁺⁺	⁺	⁺⁺⁺⁺
	1.58	1.78	1.60	1.91	1.85	1.83	1.87	1.59	1.81	1.62	2.65

Diploids were derived from pairs of the indicated MATa (top row) and MATα (left column) strains. Polarized growth on YPD agar and G2/G1 ratio in YPD liquid were assayed as described in MATERIALS AND METHODS. Non-complementing diploids (cell elongation = ++++, G2/G1 > 2.5) are shown in bold.