Table 3.

Performance estimation of 5-fold cross validation and performance comparison with the existing methods

	Size	Combined-instance			Homolog-instance			Target-instance
		SP	SE	MCC	SP	SE	MCC	SP	SE	MCC
Positive	15,287	0.9823	0.9966	0.9790	0.9684	0.9915	0.9601	0.9820	0.9976	0.9796
Negative	15,287	0.9965	0.9821	0.9790	0.9912	0.9676	0.9601	0.9975	0.9817	0.9796
[Acc; MCC]		[98.93%; 0.9789]			[97.95%; 0.9599]			[97.95%; 0.9599]
[ROC-AUC]		[0.9933]			[0.9912]			[0.9978]
F1 Score		0.9894			0.9798			0.9897
KMM-SVM [23]		SP			SE			F1 score
① human- > mouse		0.517			0.937			0.667
② E.coli- > human		0.257			0.161			0.199

① denotes the work [23] that transfers the knowledge of Salmonella-human PPI networks to predict Salmonella-mouse protein interactions;② denotes the work [23] that transfers the knowledge of Salmonella-Ecoli PPI networks to predict Salmonella-human protein interactions