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Table 1.

Task variables that influence the sex differences in fatigability

Variables Fatigability Examples of supporting studies
Intensity of contraction
Low intensity M > F Hunter and Enoka 2001; Yoon et al. 2007; Keller et al. 2011
Low intensity strength matched M = F Hunter et al. 2004b, 2006b
Moderate intensity M > F Fulco et al. 1999; Hunter et al. 2004c, 2009
High intensity M > F Russ and Kent-Braun 2003; Hunter et al. 2006a; Martin and Rattey 2007
M = F Maughan et al. 1986; Yoon et al. 2007
Muscle group (isometric only)
Adductor pollicis M > F Fulco et al. 1999
Elbow flexors M > F Hunter et al. 2004c; Avin et al. 2010; Keller et al. 2011
Finger flexors (handgrip) M > F West et al. 1995; Hunter et al. 2006b
Elbow extensors M = F Dearth et al. 2010
Trunk flexors M = F Deering et al. 2017
Trunk extensors M > F Clark et al. 2003; Lariviere et al. 2006
Knee extensors M > F Clark et al. 2005
Ankle dorsiflexors M > F Russ and Kent-Braun 2003
M = F Kent-Braun et al. 2002; Hunter et al. 2008b; Avin et al. 2010
Velocity of contraction
Slow velocity concentric M > F Yoon et al. 2015
Moderate velocity concentric M > F Pincivero et al. 2003
High velocity concentric M = F Senefeld et al. 2013
Slow to moderate eccentric M = F Hubal et al. 2008; Lee et al. 2017
F > M Sewright et al. 2008; Power et al. 2013
Cognitive challenge imposed
Elbow flexors (isometric) F increase fatigability; M minimal change Yoon et al. 2009b; Keller-Ross et al. 2014; Pereira et al. 2015
Ankle dorsiflexors (isometric) F and M no change Vanden Noven et al. 2014

Shown are task variables that are known to alter the magnitude of the sex difference in performance fatigability during single-limb exercise, along with examples of how that variable can change and the general findings to date. Examples of supporting studies are cited in the last column although the list is not exhaustive.

F, Females; M, males.

M > F, Males are more fatigable than females.

F > M, Females are more fatigable than males.

M = F, Females are similar in fatigability.