Skip to main content
. Author manuscript; available in PMC: 2018 Jul 2.
Published in final edited form as: J Neurogenet. 2016 Nov 15;30(3-4):195–204. doi: 10.1080/01677063.2016.1252764

Figure 2.

Figure 2

Feeding of RU486 to GeneSwitch-elav/UAS-miRNA transgenic stocks alters the ethanol sensitivity of three out of seven tested miRNA overexpression lines (relative to stock not fed RU486). Shown is the fold difference in ethanol sensitivity between the RU486-fed and not fed stocks calculated using the formula in the Methods section (error bars are SEM, * indicates a P value of < 0.05). miRNAs found to be induced by ethanol are shown by open bars while miRNAs normally suppressed by ethanol are by closed bars. The open/closed bar is a transgene that encodes four miRNAs: miR-310 was induced by ethanol and miR-313 was suppressed by ethanol. mir-311 and mir-312 were not found to be ethanol-responsive. The mir-310∼313 transgene induces all four of these miRNAs. The mir-61,2,3 transgene induces all 3 mir-6 paralogs.