Table 3. Gene ontology annotations for miR-6 targets.

Annotation cluster	Enrichment score	GO Term: Biological Function	Gene Count	% of total	P-Value	FE	BS	FDR
1	3.84	instar larval or pupal morphogenesis	23	6.42	0.00	2.62	0.00	0.10
2	3.63	neuron projection morphogenesis	20	5.59	0.00	2.76	0.00	0.17
3	3.46	post-embryonic organ morphogenesis	19	5.31	0.00	2.64	0.01	0.47
4	2.93	imaginal disc-derived appendage morphogenesis	16	4.47	0.00	2.64	0.02	1.66
5	2.39	imaginal disc-derived wing morphogenesis	14	3.91	0.00	2.54	0.05	5.43
6	1.66	negative regulation of transcription	12	3.35	0.02	2.29	0.16	22.50
7	1.54	negative regulation of macromolecule biosynthetic process	13	3.63	0.02	2.09	0.21	30.00
8	1.50	leg segmentation	4	1.12	0.01	9.29	0.10	12.63
9	1.37	response to other organism	9	2.51	0.02	2.73	0.17	24.13
10	1.35	cell migration	10	2.79	0.03	2.26	0.26	41.86

Significant biological function categories were clustered based on enrichment scores using DAVID. The top term in each of the top-10 cluster is listed. The ‘Gene Count’ column displays number of genes in each cluster associated with a particular GO term, as well as the % of the total number of genes in the cluster is shown. P-value, Fold Enrichment (FE), Benjamini Score (BS) and False Discovery Rate (FDR) are also shown.