Table 4. Gene ontology annotations for miR-310 targets.
Annotation cluster | Enrichment score | GO Term: Biological Function | Gene Count | % of total | P-Value | FE | BS | FDR |
---|---|---|---|---|---|---|---|---|
1 | 6.06 | morphogenesis of an epithelium | 21 | 6.33 | 0.00 | 3.86 | 0.00 | 0.00 |
2 | 4.69 | maginal disc-derived appendage morphogenesis | 19 | 5.72 | 0.00 | 3.29 | 0.00 | 0.03 |
3 | 3.43 | branching involved in open tracheal system development | 7 | 2.11 | 0.00 | 7.43 | 0.01 | 0.50 |
4 | 2.90 | imaginal disc-derived wing hair organization | 6 | 1.81 | 0.00 | 7.52 | 0.02 | 1.72 |
5 | 2.41 | neuron projection morphogenesis | 16 | 4.82 | 0.00 | 2.32 | 0.05 | 5.99 |
6 | 2.32 | positive regulation of cellular biosynthetic process | 11 | 3.31 | 0.00 | 2.98 | 0.04 | 6.02 |
7 | 2.15 | muscle cell development | 6 | 1.81 | 0.00 | 5.52 | 0.05 | 6.82 |
8 | 2.11 | positive regulation of transcription | 9 | 2.71 | 0.01 | 3.21 | 0.07 | 10.54 |
9 | 1.73 | establishment of planar polarity | 6 | 1.81 | 0.02 | 4.07 | 0.13 | 22.45 |
10 | 1.46 | epithelial cell migration | 4 | 1.20 | 0.03 | 5.71 | 0.22 | 41.09 |
Significant biological function categories were clustered based on enrichment scores using DAVID. The top term in each of the top-10 cluster is listed. The ‘Gene Count’ column displays number of genes in each cluster associated with a particular GO term. Percentage of the total number of genes in the cluster, P-value, Fold Enrichment (FE), Benjamini Score (BS) and False Discovery Rate (FDR) are also shown.