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. Author manuscript; available in PMC: 2019 Jun 15.
Published in final edited form as: Cancer Res. 2018 Apr 26;78(12):3375–3385. doi: 10.1158/0008-5472.CAN-17-3464

Figure 5.

Figure 5

Associations between gene expression, DNA copy number, DNA methylation, and microRNA expression in head and neck squamous cell carcinoma. Gene-level Pearson correlation coefficients were computed based on expression values, quantitative DNA copy number measurements, binary DNA methylation values, and expression levels of targeting microRNAs (miRNAs). For each platform the largest 1000 (DNA copy number) or smallest 1000 (DNA methylation, miRNA expression) Pearson correlation coefficients were identified. 1871 of these genes yielded Pearson correlation coefficients for all three platforms. The three squared correlation coefficients (ρ2) for each gene are plotted after ordering the genes according to (A) largest overall gene-level value of ρ2, (B) gene-level value of ρ2 for DNA copy number, (C) gene-level value of ρ2 for DNA methylation, or (D) gene-level value of ρ2 for miRNA expression.