Table 5.
Neonatal Disease by Maternal Antibiotic Indication
| No Antibiotics (n=218) |
CS Prophylaxis Only (n=33) |
GBS Prophylaxis Only (n=83) |
Premature Rupture of Membranes Only (n=107) |
All other indications for antibiotics (n=139) |
|
|---|---|---|---|---|---|
|
| |||||
| NEC | 25 (11.4%) | 2 (6.1%) | 3 (3.6%) | 7 (6.5%) | 7 (5.0%) |
| OR = 1.00 | OR = 0.49 | OR = 0.29 | OR = 0.54 | OR = 0.41 | |
| Referent | (0.11–2.21) | (0.08–0.99) | (0.23–1.29) | (0.17–0.97) | |
| P = 0.36 | P = 0.05 | P = 0.17 | P = 0.04 | ||
|
| |||||
| LOS | 16 (7.3%) | 6 (15.1%) | 12 (14.5%) | 12 (11.2%) | 19 (13.6%) |
| OR = 1.00 | OR = 2.25 | OR = 2.13 | OR = 1.59 | OR = 2.10 | |
| Referent | (0.77–6.63) | (0.96–4.73) | (0.73–3.50) | (1.05–4.21) | |
| P = 0.14 | P = 0.06 | P = 0.25 | P =0.04 | ||
|
| |||||
| Death | 26 (11.9%) | 1 (3.0%) | 7 (8.4%) | 7 (6.5%) | 15 (10.7%) |
| OR = 1.00 | OR = 0.23 | OR = 0.68 | OR = 0.52 | OR = 0.88 | |
| Referent | (0.03–1.76) | (0.28–1.63) | (0.22–1.23) | (0.45–1.74) | |
| P = 0.16 | P = 0.39 | P = 0.14 | P =0.73 | ||
|
| |||||
| NSD | 50 (22.9%) | 8 (24.2%) | 19 (22.9%) | 19 (17.8%) | 28 (20.1%) |
| OR = 1.00 | OR = 1.07 | OR = 0.99 | OR = 0.73 | OR = 0.84 | |
| Referent | (0.45–2.53) | (0.55–1.82) | (0.40–1.31) | (0.49–1.41) | |
| P = 0.87 | P = 0.99 | P =0.29 | P =0.51 | ||
Parentheses indicate the 95% confidence interval