Figure 1.

Current and next generation practice in exercise oncology.

Current practice (left column) stratifies patients based on tumor type, provides a generic exercise prescription (typically based on predicted maximum heart rate), resulting in a heterogeneous response. Next generation practice (right column) stratifies patients based on multiple factors, provides a targeted exercise prescription based on phenogroup, resulting in optimized efficacy, safety, and tolerability of exercise therapy. CPET, cardiorespiratory exercise test, CRF, cardiorespiratory fitness, Rx, prescription.