. 2018 Jul 2;13(7):e0199763. doi: 10.1371/journal.pone.0199763

Table 1. Clinical symptoms and viral load parameters in norovirus-positive patients with and without RNAemia, from children hospitalized for acute gastroenteritis in Belém, Brazil, from March / 2012 to June / 2015.

Clinical Parameter	NoV+ With RNAemia (n = 22)^c	NoV+ Without RNAemia (n = 86)^c	p value
Length of hospitalization (in days)^a	5,5 (n = 18)^d	4 (n = 65)^e^;	0.0252^b
Time of illnes (in days)^a	2 (n = 18)^d	2 (n = 65)^e	0.1605
Duration of diarrhea (in days)^a	2 (n = 18)^d	2 (n = 65)^e	0.7403
Number of Diarrheal episodes(per day)^a	4 (n = 18)^d	5 (n = 66)^e	0.2569
Duration of vomiting (in days)^a	2 (n = 18)^d	2 (n = 64)^e	0.9152
Number of vomiting episodes (per day)^a	6 (n = 18)^d	4 (n = 66)^e	0.0811
Viral load (c/g of feces)^a	7.54x10⁹ (n = 22)	3.93x10⁸ (n = 84)^f	<0.0001^b

^a Median values

^b Level of significance p ≤ 0,05

^c Total number of samples obtained

^d Number of samples effectively analyzed excluding rotavirus co-infections (n = 4)

^e Number of samples effectively analyzed excluding rotavirus co-infections (n = 18) or samples with no available information

^f Number of faecal samples quantified, excluding two samples positive for GI genogroup.