Table 2. Basic information regarding the E. oleracea extract used in the in vivo experimental models.
| Fraction | Origin of açaí | Dosing | Diluent and placebo | Administration | Posology | Reference |
|---|---|---|---|---|---|---|
| Juiceb | Not mentioned | 0.1 mg/0.15mL | Saline | Oral (gavage) and IP | 1 daily dose over 7 days | Schauss et al. 2010a |
| Not mentioned | 5,000 and 20,000 mg/kg | Not mentioned | Oral (gavage) | Single dose | Schauss et al. 2010a | |
| Not mentioned | 10,000; 20,000 and 40,000 mg/kg | Saline | Oral (gavage) | 1 daily dose over 90 days | Schauss et al. 2010a | |
| Oil | Brazil (Amapá) | 30, 100 and 300 mg/kg | Tween | Oral (gavage) | 1 daily dose over 14 days | Marques et al. 2016 |
| Not mentioned | 50 mg/mL | PBS | Intratumoral | Five applications within 15 days (1, 4, 7, 10 and 13 days) |
Monge-Fuentes et al. 2017 | |
| Pulp | Brazil | 5% | AIN diet | Oral (diet) | 35 weeks | Stoner et al. 2010 |
| Brazil (SP) | 3,330; 10,000 and 16,670 mg/kg | Saline | Oral (gavage) | Single dose | Ribeiro et al. 2010a | |
| Brazil (SP) | 3,330; 10,000 and 16,670 mg/kg | Distilled water | Oral (gavage) | 1 daily dose over 14 days | Ribeiro et al. 2010a | |
| Brazil (Pará) | 2.5% and 5% | Standard diet | Oral (diet) | 10 weeks | Fragoso et al. 2012 and 2013a | |
| Brazil (Pará) | 5% | Standard diet | Oral (diet) | 20 weeks | Fragoso et al. 2013a | |
| Brazil (Pará) | 2.5% and 5% | Diet formulatedc | Oral (diet) | 14 weeks | Choi et al. 2017 | |
| Seed | Brazil | 100 and 200 mg/mL | Ethanol-water | Oral (gavage) | 1 daily dose over 14 days | Nascimento et al. 2016 |
AIN = American Institute of Nutrition; IP = intraperitoneal; SP = São Paulo; PBS = Phosphate buffered saline.
a A reference can have different methods of administration of açaí.
bJuice of MonaVie Active® = In addition to açaí, contains lesser amounts of 19 fruits and berries.
cA cereal-based commercial diet for mice formulated by the Orient Bio Group (Seongnam, Korea).