Table 1. Baseline characteristics.
Clinical characteristics | SSII ≤17 (n = 209) | 17< SSII ≤24 (n = 210) | SSII >24 (n = 209) | p value |
---|---|---|---|---|
Age—yrs, ± sd | 52.9 ± 7.8 | 61.5 ± 8.1 | 69.0 ± 9.2 | <0.001 |
Men, n (%) | 204 (97.6) | 163 (77.6) | 109 (52.2) | <0.001 |
Diabetes mellitus, n (%) | 28 (13.4) | 40 (19.0) | 49 (23.4) | 0.051 |
Hypertension, n (%) | 91 (34.5) | 112 (53.3) | 134 (64.1) | <0.001 |
Hypercholesterolemia, n (%) | 96 (45.9) | 120 (57.1) | 127 (60.8) | 0.025 |
Current smoking, n (%) | 88 (42.3) | 60 (28.6) | 47 (22.5) | <0.001 |
Previous MI, n (%) | 55 (26.3) | 57 (27.1) | 64 (30.6) | 0.48 |
Previous PCI, n (%) | 58 (27.8) | 65 (31.0) | 60 (28.7) | 0.74 |
Previous CVA, n (%) | 10 (4.8) | 10 (4.8) | 18 (8.6) | 0.16 |
History of PAD, n (%) | 0 (0.0) | 0 (0.0) | 46 (22.0) | <0.001 |
History of renal insufficiency, n (%) | 6 (2.9) | 4 (1.9) | 20 (9.6) | <0.001 |
History of heart failure, n (%) | 1 (0.5) | 2 (1.0) | 10 (4.8) | 0.003 |
COPD, n (%) | 1 (0.5) | 9 (4.3) | 23 (11.0) | <0.001 |
Serum creatinine—μmol/L, ± sd | 77.3 ± 13.2 | 74.8 ± 17.3 | 84.6 ± 28.3 | <0.001 |
Creatinine clearance—ml/min, ± sd | 127.8 ± 31.8 | 111.9 ± 34.3 | 80.1 ± 27.8 | <0.001 |
LVEF, n (%) | <0.001 | |||
Good LVEF ≥50% | 189 (90.4) | 156 (74.2) | 136 (65.1) | |
Moderate LVEF 40–49% | 20 (9.6) | 54 (25.8) | 65 (31.1) | |
Poor LVEF <40% | 0 (0.0) | 0 (0.0) | 8 (3.8) | |
Angiographic characteristics | ||||
Indication for angiography, n (%) | 0.16 | |||
Acute MI | 77 (36.8) | 64 (30.6) | 51 (24.4) | |
Unstable angina | 58 (27.8) | 57 (27.3) | 61 (29.2) | |
Stable angina | 74 (35.4) | 99 (47.4) | 97 (46.4) | |
Coronary artery disease, n (%) | 0.007 | |||
1-vessel disease | 146 (69.9) | 118 (56.5) | 115 (55.0) | |
2-vessel disease | 63 (30.1) | 92 (43.5) | 94 (45.0) | |
Median SS [IQR] | 5.0 [3.0–9.0] | 9.0 [5.0–13.5] | 9.0 [5.0–15.0] | <0.001 |
CI: confidence interval; COPD: Chronic obstructive pulmonary disease; CVA: Cerebrovascular accident; IQR: inter quartile range; LVEF: left ventricular ejection fraction; MI: Myocardial infarction; PAD: Peripheral artery disease; PCI: Percutaneous coronary intervention; sd: standard deviation; SS: SYNTAX score; SSII: SYNTAX score II; yrs: years.