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. 2018 Jul 2;13(7):e0200076. doi: 10.1371/journal.pone.0200076

Table 1. Baseline characteristics.

Clinical characteristics SSII ≤17 (n = 209) 17< SSII ≤24 (n = 210) SSII >24 (n = 209) p value
Age—yrs, ± sd 52.9 ± 7.8 61.5 ± 8.1 69.0 ± 9.2 <0.001
Men, n (%) 204 (97.6) 163 (77.6) 109 (52.2) <0.001
Diabetes mellitus, n (%) 28 (13.4) 40 (19.0) 49 (23.4) 0.051
Hypertension, n (%) 91 (34.5) 112 (53.3) 134 (64.1) <0.001
Hypercholesterolemia, n (%) 96 (45.9) 120 (57.1) 127 (60.8) 0.025
Current smoking, n (%) 88 (42.3) 60 (28.6) 47 (22.5) <0.001
Previous MI, n (%) 55 (26.3) 57 (27.1) 64 (30.6) 0.48
Previous PCI, n (%) 58 (27.8) 65 (31.0) 60 (28.7) 0.74
Previous CVA, n (%) 10 (4.8) 10 (4.8) 18 (8.6) 0.16
History of PAD, n (%) 0 (0.0) 0 (0.0) 46 (22.0) <0.001
History of renal insufficiency, n (%) 6 (2.9) 4 (1.9) 20 (9.6) <0.001
History of heart failure, n (%) 1 (0.5) 2 (1.0) 10 (4.8) 0.003
COPD, n (%) 1 (0.5) 9 (4.3) 23 (11.0) <0.001
Serum creatinine—μmol/L, ± sd 77.3 ± 13.2 74.8 ± 17.3 84.6 ± 28.3 <0.001
Creatinine clearance—ml/min, ± sd 127.8 ± 31.8 111.9 ± 34.3 80.1 ± 27.8 <0.001
LVEF, n (%) <0.001
Good LVEF ≥50% 189 (90.4) 156 (74.2) 136 (65.1)
Moderate LVEF 40–49% 20 (9.6) 54 (25.8) 65 (31.1)
Poor LVEF <40% 0 (0.0) 0 (0.0) 8 (3.8)
Angiographic characteristics
Indication for angiography, n (%) 0.16
Acute MI 77 (36.8) 64 (30.6) 51 (24.4)
Unstable angina 58 (27.8) 57 (27.3) 61 (29.2)
Stable angina 74 (35.4) 99 (47.4) 97 (46.4)
Coronary artery disease, n (%) 0.007
1-vessel disease 146 (69.9) 118 (56.5) 115 (55.0)
2-vessel disease 63 (30.1) 92 (43.5) 94 (45.0)
Median SS [IQR] 5.0 [3.0–9.0] 9.0 [5.0–13.5] 9.0 [5.0–15.0] <0.001

CI: confidence interval; COPD: Chronic obstructive pulmonary disease; CVA: Cerebrovascular accident; IQR: inter quartile range; LVEF: left ventricular ejection fraction; MI: Myocardial infarction; PAD: Peripheral artery disease; PCI: Percutaneous coronary intervention; sd: standard deviation; SS: SYNTAX score; SSII: SYNTAX score II; yrs: years.