Table 2.
Univariate Logistic Analysis for Recurrence and Death After Lung Cancer Surgery.
| Variable | Recurrence | 95% Confidence Interval | Death | 95% Confidence interval | ||||
|---|---|---|---|---|---|---|---|---|
| HR | Lower | Upper | P Value | HR | Lower | Upper | P Value | |
| Sex | ||||||||
| Male | 1.000 | 1.000 | ||||||
| Female | 0.839 | 0.632 | 1.115 | .227 | 0.515 | 0.405 | 0.657 | <.001 |
| Age, years | 1.004 | 0.991 | 1.017 | .571 | 1.046 | 1.033 | 1.058 | <.001 |
| Body mass index, kg/m2 | 1.038 | 0.989 | 1.089 | .132 | 0.934 | 0.899 | 0.971 | .001 |
| ASA | ||||||||
| 1 | 1.000 | 1.000 | ||||||
| 2 | 1.437 | 1.030 | 2.003 | .033 | 1.416 | 1.084 | 1.849 | .011 |
| 3 | 1.248 | 0.757 | 2.059 | .385 | 2.142 | 1.513 | 3.033 | <.001 |
| Histology | ||||||||
| Squamous cell | 1.000 | 1.000 | ||||||
| Adenocarcinoma | 0.704 | 0.525 | 0.945 | .019 | 0.565 | 0.447 | 0.713 | <.001 |
| Othersa | 0.299 | 0.162 | 0.553 | <.001 | 0.690 | 0.490 | 0.971 | .033 |
| Type of operation I | ||||||||
| VATS | 1.000 | 1.000 | ||||||
| Open thoracotomy | 2.233 | 1.705 | 2.925 | <.001 | 2.037 | 1.644 | 2.524 | <.001 |
| Type of operation II | ||||||||
| Lobectomy | 1.000 | 1.000 | ||||||
| Segmentectomy | 0.000 | 0.000 | .992 | 0.270 | 0.101 | 0.725 | .009 | |
| Wedge resection | 0.332 | 0.164 | 0.673 | .002 | 0.593 | 0.382 | 0.923 | .021 |
| Preoperative hypertension | 1.102 | 0.786 | 1.545 | .572 | 0.898 | 0.675 | 1.195 | .460 |
| Preoperative diabetes mellitus | 1.209 | 0.763 | 1.917 | .419 | 1.055 | 0.712 | 1.564 | .788 |
| Preoperative stroke history | 0.655 | 0.308 | 1.392 | .271 | 0.843 | 0.484 | 1.468 | .546 |
| Preoperative IHD history | 0.778 | 0.399 | 1.516 | .461 | 1.335 | 0.858 | 2.079 | .200 |
| Preoperative COPD history | 0.623 | 0.256 | 1.512 | .295 | 1.125 | 0.679 | 1.866 | .648 |
| Tumor | ||||||||
| 0-1 | 1.000 | 1.000 | ||||||
| 2 | 3.986 | 2.808 | 5.658 | <.001 | 2.170 | 1.706 | 2.762 | <.001 |
| 3 | 7.711 | 4.849 | 12.264 | <.001 | 3.723 | 2.565 | 5.404 | <.001 |
| 4 | 8.803 | 5.256 | 14.744 | <.001 | 5.578 | 3.778 | 8.237 | <.001 |
| Node | ||||||||
| 0 | 1.000 | 1.000 | ||||||
| 1 | 75.275 | 41.354 | 137.018 | <.001 | 2.133 | 1.637 | 2.778 | <.001 |
| 2 | 100.4422 | 54.814 | 184.053 | <.001 | 2.924 | 2.222 | 3.849 | <.001 |
| Adjuvant radiotherapy | 0.308 | 0.232 | 0.408 | <.001 | 0.309 | 0.246 | 0.387 | <.001 |
| Adjuvant chemotherapy | 0.632 | 0.416 | 0.960 | .031 | 0.816 | 0.577 | 1.152 | .248 |
| Surgery time (minutes) | 1.004 | 1.002 | 1.005 | <.001 | 1.004 | 1.003 | 1.005 | <.001 |
| Anesthesia time (minutes) | 1.004 | 1.003 | 1.006 | <.001 | 1.004 | 1.003 | 1.005 | <.001 |
| Years at surgery | ||||||||
| 2003-2006 | 1.000 | 1.000 | ||||||
| 2007-2009 | 0.952 | 0.659 | 1.374 | .792 | 0.912 | 0.695 | 1.196 | .505 |
| 2010-2012 | 0.882 | 0.603 | 1.289 | .516 | 0.660 | 0.484 | 0.899 | .009 |
| Intraoperative pRBC transfusion | 1.460 | 1.020 | 2.089 | .039 | 1.606 | 1.224 | 2.107 | .001 |
| Postoperative complication | 1.014 | 0.600 | 1.714 | .959 | 1.393 | 0.966 | 2.009 | .076 |
| Clavien-Dindo classification | ||||||||
| None | 1.000 | 1.000 | ||||||
| I, II | 1.124 | 0.627 | 2.013 | .695 | 1.392 | 0.916 | 2.115 | .121 |
| IIIA, IIIB | 0.369 | 0.092 | 1.485 | .160 | 1.033 | 0.512 | 2.084 | .928 |
| IVA, IVB | 0.815 | 0.114 | 5.812 | .838 | 0.969 | 0.241 | 3.897 | .965 |
Abbreviations: ASA, American Society of Anesthesiologists; COPD, chronic obstructive pulmonary disease; HR, hazard ratio; IHD, ischemic heart disease; RBC, red blood cell; VATS, video-assisted thoracic surgery.
a Others: Large cell type, sarcomatoid lung cancer.