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. 2018 Apr 24;209(3):845–859. doi: 10.1534/genetics.118.300840

Table 4. Summary of genotype frequencies in M. m. musculus backcross.

Crosses AA AB Total %AB P-value
Region 1 musculusCZII × PWK sire 100 93 195 47.7 0.614
140,089,156– females 54 50 106 47.2 0.695
141,037,913 bp males 46 43 89 48.3 0.75
musculusPWK × CZII sire 144 157 301 52.2 0.454
females 77 83 160 51.9 0.635
males 67 74 141 52.5 0.556
Total 244 250 496 50.4 0.787
Region 2 musculusCZII × PWK sire 97 97 195 49.7 1
148,602,050– females 53 53 106 50 1
151,609,913 bp males 44 44 89 49.4 1
musculusPWK × CZII sire 138 162 301 53.8 0.166
females 73 86 160 53.8 0.303
males 65 76 141 53.9 0.354
total 235 259 496 52.2 0.28

To test for TRD within M. m. musculus, female musculusPWK were crossed to reciprocal interstrain F1s between musculusCZII and musculusPWK. Offspring were genotyped for two regions inside the introgressed TRD on Chr 4. AA and AB represent offspring genotype.