. 2018 Jun 28;209(3):651–673. doi: 10.1534/genetics.118.300291

Table 3. Genetically-defined functions of C. elegans microRNA genes.

Conserved family	MicroRNA	Function	Target(s)	References
nc	mir-60	Oxidative stress	zip-10	Kato et al. (2016)^a
nc	mir-61	Vulva development	vav-1	Yoo and Greenwald (2005)^a
	mir-64-66, mir-229	Heat stress		Nehammer et al. (2015)^a
nc	mir-67	Avoidance of P. aeruginosa	sax-7	Ma et al. (2017)^a
	mir-70	Survival on P. aeruginosa		Kudlow et al. (2012)^a
mir-71	mir-71	L1 diapause survival	age-1; unc-31	Zhang et al. (2011)^a
		Post L1 diapause developmental timing	hbl-1; lin-42	Zhang et al. (2011)^a
		AWC left/right specification	tir-1	Hsieh et al. (2012)^a
		Life span		de Lencastre et al. (2010)^a, Boulias and Horvitz (2012)
		Heat stress		Nehammer et al. (2015)^a
nc	mir-73-74	Adult viability		Brenner et al. (2010)^a
nc	mir-79	Neuronal migration	sqv-5; sqv-7	Pedersen et al. (2013)^a
mir-29	mir-83	Gonadal morphogenesis	cdc-42; pat-3	Brenner et al. (2010)^a, Burke et al. (2015); Burke et al. (2015)
mir-124	mir-124	Dauer formation		Than et al. (2013)^a
mir-124	mir-124	Gonadal morphogenesis		Brenner et al. (2010)^a
nc	mir-228	Embryonic viability		Brenner et al. (2010)^a
nc	mir-233	Survival on P. aeruginosa	sca-1	Dai et al. (2015)^a
nc	mir-234	Dauer formation		Than et al. (2013)^a
mir-92	mir-235	Adult viability		Brenner et al. (2010)^a
mir-92	mir-235	L1 diapause arrest	nhr-91	Kasuga et al. (2013)^a
nc	mir-238	Nicotine signaling	acr-19	Rauthan et al. (2017)^a
nc		Life span		de Lencastre et al. (2010)^a
nc	mir-239	Life span		de Lencastre et al. (2010)^a
nc	mir-246	Life span		de Lencastre et al. (2010)^a
nc	mir-251, mir-252	Survival on P. aeruginosa		Kudlow et al. (2012)^a
nc	mir-259	Gonadal morphogenesis		Brenner et al. (2010)^a
	mir-273	ASE left/right specification	die-1	Chang et al. (2004)^a
mir-365	mir-786	Defecation cycle length	elo-2	Miska et al. (2007)^a, Kemp et al. (2012)
	mir-791	CO₂ sensing	akap-1^a; cah-3^b	Drexel et al. (2016)^a

Where there is more than one target and more than one reference, references are listed in the order of the targets in the preceding column.

Denotes the reference(s) that first reported the function.

In the first column, nc denotes microRNAs that are not members of well conserved seed families.